Document classification for mining host pathogen protein–protein interactions
نویسندگان
چکیده
منابع مشابه
Mining Host-Pathogen Interactions
containing HPI information and another abstract that does not. Using a training set of pre-annotated abstracts, the system can then learn how to efficiently discriminate between these two abstract types. Moreover, the same characteristic features can be calculated for the individual sentences in the abstract. Thus, we can use the same supervised-learning approach to solve Tasks 1 and 2. Finally...
متن کاملMultitask learning for host–pathogen protein interactions
MOTIVATION An important aspect of infectious disease research involves understanding the differences and commonalities in the infection mechanisms underlying various diseases. Systems biology-based approaches study infectious diseases by analyzing the interactions between the host species and the pathogen organisms. This work aims to combine the knowledge from experimental studies of host-patho...
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www.sciencedirect.com Microbial infections are characterized by a continual dramatic interplay between pathogen and host: pathogens exploit an array of host cell functions during infection and their hosts respond with appropriate immune responses. Host–pathogen interactions are complex and dynamic by nature and are generally analyzed with a reductionist approach focusing on one facet of the int...
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The threat posed to human health by arthropod-borne bacteria is most vividly demonstrated by the devastating epidemics caused by the plague. The diversity of pathogenic bacteria spread by arthropods is probably underestimated. Recently recognized infectious diseases such as Lyme disease and ehrlichiosis are caused by bacteria transmitted by arthropods. Bacteria which alternate between arthropod...
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In the context of host-pathogen interaction, host cell receptors and signaling pathways are essential for both invading pathogens, which exploit them for their own profit, and the defending organism, which activates early mechanism of defense, known as innate immunity, to block the aggression. Because of their central role as scaffolding proteins downstream of activated receptors, β-arrestins a...
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ژورنال
عنوان ژورنال: Artificial Intelligence in Medicine
سال: 2010
ISSN: 0933-3657
DOI: 10.1016/j.artmed.2010.04.003